Q12. Can I have data on Genome browser from different experiments?

Data from different experiments can be plotted on Genome Browser. To view the data, drag and drop the entity lists of interest on Genome Browser, it will be added as a track and can be viewed along with the other existing tracks.

Q11. How can I find a specific gene in Genome Browser?

To find a specific Gene or probe in Genome Browser, go to spreadsheet and use “Find” option. The selected entity will be highlighted in the spreadsheet as well as the tracks.

Q10. Can I export data specific for a chromosomal region?

Yes, data from a specific region can be exported from Genome Browser in following two ways:

  1. From spreadsheet:  Follow the steps below for the same:
  • Select the region of interest
  • Go to Spreadsheet
  • Right-click on the spreadsheet and select Export as entity list/ Export as text.
  1. From Data Track :  Right-click on track for export options.

Q9. Can I select a specific region of interest in a chromosome?

Yes, you can select a specific region in a chromosome in either of the following ways:
 
a. Enter the region of interest in the chromosomal coordinates
b. Browse through the chromosome : Below are the options to browse through the chromosome in Genome Browser:

  1. Use zoom function from tool bar
  2. Use double click to zoom in and shift+double click to zoom out.
  3. Use shift + mouse drag to zoom in.

Q8. I have created an Organism by mistake. Can I delete it?

To delete an organism created from “Annotations -> Annotation Manager”, please go to the Annotations Manager -> Select the Organism -> Click Delete.

Q7. I don’t have internet connection to download the builds from Agilent server. How can I proceed?

You may contact GeneSpring support to obtain a file based update. After the file based update is obtained, please go to “Annotations -> Annotations Manager -> List -> From file -> Select the .update file”. It will list all the annotations present in the update file, select the interested ones and click update.

Q6. What file types are supported for creating a build?

GeneSpring supports .tsv,.txt and .gz files for a build creation.

Q5. What information is required in a file for creating build in GeneSpring?

Chromosome name and length without any header should be present in a file for creating a build. For example
chr1    24336437
chr2    35347543

Q4. I don’t see build for my organism of interest on Agilent server. How do I proceed with Genome Browser?

GeneSpring provides you with the option to create your organism and build in the tool.
 
Create Organism
•Go to “Annotations -> Annotations Manager -> Create”
•Select “New Organism”
•Enter Common name, Scientific name and Taxonomy ID
 
Create New Build
•Go to “Annotations -> Annotation Manager -> Click on the Organism of interest -> Create”
•Select “New Build”

Q3. I get a message “No Genome Build found for organism Homo sapiens” while trying to use Genome Browser. How can I run Genome Browser?

To run Genome Browser, please download the build for the organism of your experiment. To download a build go to “Annotations -> Annotation Manager -> List -> From server”. Select the Organism and build of your interest and download them and then try to run Genome Browser.

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